Associations of inflammatory cytokines and cortisol with nonmotor features of Huntington's disease.

Hiba Bilal Stuart J McDonaldJulie C StoutIan H Harding

Published in: Annals of clinical and translational neurology (2024)

Peripheral inflammation is associated with depression symptoms and cognitive impairment in HD. Our findings suggest that interactions between the immune and nervous systems are important in HD, and highlight the potential of chronic inflammation as a therapeutic target in early stages of HD.

Keyphrases

cognitive impairment
oxidative stress
sleep quality
parkinson disease
depressive symptoms
risk assessment
human health
climate change
chemotherapy induced