Microglial morphology in the somatosensory cortex across lifespan. A quantitative study.

Sanziana GodeanuDevin ClarkeLaura StopperAlexandru-Florian DeftuAurel Popa-WagnerAdrian Tudor BălșeanuAnja SchellerCatalin Bogdan

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2023)

Our study provides insight into microglia morphology changes across lifespan under physiological conditions. We were able to highlight, that due to the dynamic nature of microglia several morphological parameters are needed to establish the physiological state of these cells.

Keyphrases

inflammatory response
neuropathic pain
induced apoptosis
cell proliferation
cell death
functional connectivity
endoplasmic reticulum stress