The role of HLA-DR on plasmacytoid dendritic cells in mediating the effects of Butyrivibrio gut microbiota on Parkinson's disease.

Zihao WangHuan XiaTingting FengAdilai AibibuliMingyang ZhangXin-Ling Yang

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2024)

Our study emphasizes the complex interactions between the gut microbiota, immune characteristics, and PD. The relationships and intermediary roles identified in our research provide important insights for developing potential therapies that target the gut microbiome to alleviate symptoms in PD patients.

Keyphrases

dendritic cells
immune response
end stage renal disease
regulatory t cells
newly diagnosed
ejection fraction
peritoneal dialysis
risk assessment
depressive symptoms
human health
physical activity
patient reported