Macrolides mediate transcriptional activation of the msr(E)-mph(E) operon through histone-like nucleoid-structuring protein (HNS) and cAMP receptor protein (CRP).

Yitao DuanShuangqing LiuYuting GaoPeng ZhangDaqing MaoYi Luo

Published in: The Journal of antimicrobial chemotherapy (2021)

Macrolides could activate transcription of the msr(E)-mph(E) operon through HNS and CRP in K. pneumoniae and E. coli, and this might occur in diverse species of bacteria.

Keyphrases

binding protein
transcription factor
protein protein
escherichia coli
dna methylation
gene expression
amino acid
heat shock