Endothelium-Specific Deficiency of Polycystin-1 Promotes Hypertension and Cardiovascular Disorders.
Mouad HamzaouiDeborah GroussardDorian NezamZoubir DjeradaGaspard LamyVirginie TardifAnais DumesnilSylvanie RenetValery BrunelDorien J M PetersLaurence ChevalierMélanie HanoyPaul MulderVincent RichardBellien JeremyDominique GuerrotPublished in: Hypertension (Dallas, Tex. : 1979) (2022)
in endothelial cells promotes endothelial dysfunction and hypertension, impairs arteriovenous fistula development, and potentiates the cardiovascular alterations associated with chronic kidney disease.