Molecular Subtypes of Head and Neck Cancer in Patients of African Ancestry.
Nadia MezghaniAlexandria YaoDaria VasilyevaNicole KaplanAustin ShackelfordAngela J YoonElizabeth PhiliponeSunil DubeyGary K SchwartzAlison M TaylorFatemeh Momen-HeraviPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Novel genomic modifications and molecular signatures may be related to environmental, social, and behavioral factors associated with racial disparities in HNC. Unique tumor mutations and biological pathways have potential clinical utility in providing more targeted and individualized screening, diagnostic, and treatment modalities to improve health outcomes.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- healthcare
- prognostic factors
- mental health
- single molecule
- cancer therapy
- copy number
- patient reported outcomes
- gene expression
- dna methylation
- climate change
- drug delivery
- combination therapy
- african american
- patient reported
- drug induced