PDGF-AA guides cell crosstalk between human dental pulp stem cells in vitro via the PDGFR-α/PI3K/Akt axis.

Siqun XuJieya WeiYang LiuLi ZhangMengmeng DuanJiazhou LiZhixing NiuXiaohua PuMinglei HuangHao ChenXuedong ZhouJing Xie

Published in: International endodontic journal (2024)

This research demonstrated that PDGF-AA can enhance Cx43-mediated GJIC in DPSCs via the PDGFR-α/PI3K/Akt axis, which provides new cues for dental pulp regeneration from the perspective of intercellular communication.

Keyphrases

pi k akt
stem cells
signaling pathway
cell therapy
cell proliferation
cell cycle arrest
smooth muscle
endothelial cells
vascular smooth muscle cells
single cell
induced pluripotent stem cells
bone marrow