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Semaglutide 2.4 mg for the Treatment of Obesity: Key Elements of the STEP Trials 1 to 5.

Robert F KushnerSalvatore CalannaMelanie DaviesDror DickerW Timothy GarveyBryan GoldmanIldiko LingvayMette ThomsenThomas A WaddenSean WhartonJohn P H WildingDomenica Rubino
Published in: Obesity (Silver Spring, Md.) (2020)
The STEP program evaluates the efficacy and safety of semaglutide 2.4 mg subcutaneously once weekly in a broad population. The trials will provide insights on WM in people with obesity with and without type 2 diabetes and on long-term follow-up.
Keyphrases
  • type diabetes
  • insulin resistance
  • metabolic syndrome
  • weight loss
  • high fat diet induced
  • weight gain
  • glycemic control
  • cardiovascular disease
  • adipose tissue
  • quality improvement
  • combination therapy