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Role of the mitophagy-apoptosis axis in the pathogenesis of polycystic ovarian syndrome.

Hiroshi KobayashiHiroshi ShigetomiSho MatsubaraChiharu YoshimotoShogo Imanaka
Published in: The journal of obstetrics and gynaecology research (2024)
In conclusion, fetuses exposed to a hyperandrogenemic intrauterine environment may cause the PCOS phenotype possibly through disruption of the compensatory regulation of the mitophagy-apoptosis axis.
Keyphrases
  • endoplasmic reticulum stress
  • cell cycle arrest
  • oxidative stress
  • cell death
  • nlrp inflammasome
  • case report
  • type diabetes
  • gestational age
  • metabolic syndrome
  • signaling pathway
  • cell proliferation
  • preterm birth