Integrative Analysis of the IQ Motif-Containing GTPase-Activating Protein Family Indicates That the IQGAP3-PIK3C2B Axis Promotes Invasion in Colon Cancer.

Zhuo LiuXiao LiJie MaDechuan LiHaixing JuYong LiuYinbo ChenXujun HeYuping Zhu

Published in: OncoTargets and therapy (2020)

The results of our current study and corresponding previous studies provide evidence that IQGAP3 is elevated in CRC and promotes colon cancer growth and metastasis by regulating PIK3C2B activation.

Keyphrases

signaling pathway
cell migration
protein protein
network analysis