Response of eosinophilic oesophagitis to proton pump inhibitors is associated with impedance-pH parameters implying anti-reflux mechanism of action.
Marzio FrazzoniLeonardo FrazzoniNicola De BortoliSalvatore RussoSalvatore ToloneElena ArsièRita ConigliaroRoberto PenaginiEdoardo SavarinoPublished in: Alimentary pharmacology & therapeutics (2021)
Higher efficacy of oesophago-salivary reflex and more severe mucosal damage in the distal oesophagus are associated with EoE response to PPIs, implying an anti-reflux mechanism of action as most likely.