Expansion of highly interferon-responsive T cells in early-onset Alzheimer's disease.

Daniel W Sirkis Caroline Warly SolsbergTaylor P JohnsonLuke W BonhamAlexis P OddiEthan G GeierBruce L MillerGil D RabinoviciJennifer S Yokoyama

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)

Interferon-responsive T cells expanded in early-onset Alzheimer's disease (AD). Increased interferon-associated gene expression present in early- and late-onset AD. Peripheral immune changes in T and NK cells driven by females with early-onset AD.

Keyphrases

early onset
late onset
gene expression
dendritic cells
nk cells
cognitive decline
cancer therapy
dna methylation