IL-33 signalling in liver immune cells enhances drug-induced liver injury and inflammation.

Maísa Mota AntunesAlan Moreira AraújoAriane Barros DinizRafaela Vaz Sousa PereiraDébora Moreira AlvarengaBruna Araújo DavidRenata Monti RochaMaria Alice Freitas LopesSarah Cozzer MarchesiBrenda Naemi NakagakiÉrika CarvalhoPedro Elias MarquesBernhard RyffelValérie QuesniauxRodrigo Guabiraba BritoJosé Carlos Alves FilhoDenise Carmona CaraRafael Machado RezendeGustavo Batista Menezes

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2017)

Blockage of IL-33/ST2 axis reduces APAP-mediated organ injury by dampening liver chemokine release and activation of resident and infiltrating liver non-parenchymal cells.

Keyphrases

induced apoptosis
oxidative stress
patient safety
emergency department
quality improvement
cell death
endoplasmic reticulum stress
cell proliferation