A high affinity monoclonal antibody against HLA-E-VL9 enhances natural killer cell anti-tumor killing.
Joyce K HwangDaniel J MarstonDaniel WrappDapeng LiMarina TuyishimeSimon BrackenridgeBrianna RhodesMax QuastelA Brenda KapingidzaJacob GaterAustin HarnerYunfei WangWes RountreeGuido FerrariPersephone BorrowAndrew J McMichaelGeraldine M GillespieBarton F HaynesMihai L AzoiteiPublished in: bioRxiv : the preprint server for biology (2024)
A high affinity monoclonal antibody against HLA-E-VL9 enhances natural killer cell anti-tumor killing by checkpoint inhibition and antibody dependent cellular cytotoxicity.