Encouraging long-term survival following autophagy inhibition using neoadjuvant hydroxychloroquine and gemcitabine for high-risk patients with resectable pancreatic carcinoma.

Samer S AlMasriMazen S ZenatiAnnissa DesilvaIbrahim NassourBrian A BooneAatur D SinghiDavid L BartlettLance A LiottaVirginia EspinaPatricia LoughranMichael T LotzeAlessandro PanicciaHerbert J ZehAmer H ZureikatNathan Bahary

Published in: Cancer medicine (2021)

Compared to historical data, neoadjuvant autophagy inhibition with HCQ plus gemcitabine is associated with encouraging long-term survival for patients with PDAC.

Keyphrases

locally advanced
rectal cancer
squamous cell carcinoma
cell death
radiation therapy
endoplasmic reticulum stress
signaling pathway
oxidative stress
lymph node
electronic health record
big data