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[Hormones of stress-response system in alcohol dependence: the ability to predict duration of remission].

Tamara P VetluginaOlga A LobachevaValentina B NikitinaValentina D ProkopievaAnna I MandelNikolay A Bokhan
Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2020)
Dysfunctions in the spectrum of stress-realizing hormones in patients with alcohol dependence in the time course of the therapy for withdrawal syndrome and post-withdrawal state were revealed, the main of which are high level of cortisol, testosterone, reduction of secretion of free thyroxine and free triiodothyronine. Patients with unstable therapeutic remission are characterized by a high concentration of testosterone after alcohol detoxification, which allows us to consider testosterone as a biological criterion that can increase the accuracy of prediction of the duration of remission after anti-alcohol therapy.
Keyphrases
  • replacement therapy
  • alcohol consumption
  • disease activity
  • ulcerative colitis
  • systemic lupus erythematosus
  • stem cells
  • cell therapy
  • stress induced