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Surgical aspects and outcomes after nephrectomy for Wilms tumour in sub-Saharan Africa: A report from Wilms Africa Phase II-CANCaRe Africa.

William Appeadu-MensahCecilia MdokaSeifu AlemuAbiboye YifieyehTiya KaplamulaFelix OyaniaGeorge ChagalukaGersam Abera MulugetaEvaristar KudowaMulugeta YimerLorna Awo RennerVivian PaintsilInam ChitsikeElizabeth MolyneuxBarnabas AtwiineFrancine KouyaKathy Pritchard-JonesAbdelhafeez H AbdelhafeezAndient DessalegneBothwell MbuwayesangoNgock GeorgesTrijn IsraelsEric Borgstein
Published in: Pediatric blood & cancer (2024)
Survival post nephrectomy is challenged by treatment abandonment, treatment-related mortality and relapse. Large tumours after preoperative chemotherapy were associated with a higher risk of tumour rupture. Earlier diagnosis and access to radiotherapy are expected to improve survival.
Keyphrases
  • phase ii
  • clinical trial
  • free survival
  • locally advanced
  • robot assisted
  • open label
  • radiation therapy
  • cardiovascular disease
  • squamous cell carcinoma
  • combination therapy
  • double blind