Breakthrough Mpox outbreak investigation, the delicate balance between host immune response and viral immune escape.

Marco MorettiAnnelies MeuwissenAntonio M RezendeSabine ZangeEls Van NederveldeTessa de BlockKoen VercauterenThomas DemuyserSabine D Allard

Published in: Sexually transmitted diseases (2024)

Incomplete MPXV vaccination as well as MPXV variants might result in breakthrough infections. Preventive measures, such as MPVX vaccination, could maintain immunity in individuals with higher risk of MPXV infection, and might lower disease severity.

Keyphrases

immune response
sars cov
copy number
dendritic cells
inflammatory response
dna methylation