Pharmacokinetic and Tissue Distribution Profile of Long Acting Tenofovir Alafenamide and Elvitegravir Loaded Nanoparticles in Humanized Mice Model.
Pavan Kumar PrathipatiSubhra MandalGregory PonRenuga VivekanandanChristopher J DestachePublished in: Pharmaceutical research (2017)
This study documents that a TAF + EVG NP provides sustained release, which can overcome patient non-adherence to dosing and may facilitate prediction of appropriate protective drug concentration for HIV prophylaxis.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv positive
- drug delivery
- human immunodeficiency virus
- hepatitis c virus
- case report
- hiv testing
- hiv aids
- men who have sex with men
- cancer therapy
- high fat diet induced
- adipose tissue
- metabolic syndrome
- type diabetes
- wound healing
- south africa
- glycemic control
- adverse drug
- electronic health record