New Approach about the Signaling Crosstalk between IQGAPs/ NF- κB/IL-8 and PDCD5/p53/TRAIL Pathways that Modulate Malignant Transformation in Hepatocellular Carcinoma.

Khairy Mohamed ZoheirMohamed A AbdelhafezAhmed M DarwishKarima F Mahrous

Published in: Asian Pacific journal of cancer prevention : APJCP (2022)

IQGAPs have a direct signaling relationship with p53, IL-8, and TRAIL family. This interaction is recognized as a key signalling pathway for hepatocellular carcinogenesis.

Keyphrases

signaling pathway
oxidative stress
pi k akt
cell proliferation