Identifying genetic variants associated with ritodrine-induced pulmonary edema.

Seung Mi LeeYoomi ParkYoung Ju KimHan-Sung HwangHeewon SeoByung-Joo MinKye Hwa LeeSo Yeon KimYoung Mi JungSuehyun LeeChan-Wook ParkJu Han KimJoong Shin Park

Published in: PloS one (2020)

We identified new potential variants in genes that play a role in cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) regulation, which supports their putative involvement in the predisposition to ritodrine-induced pulmonary edema in pregnant women.

Keyphrases

protein kinase
pregnant women
high glucose
pulmonary hypertension
diabetic rats
drug induced
copy number
genome wide
oxidative stress
endothelial cells
transcription factor
risk assessment
binding protein
pregnancy outcomes