Mathematical Analysis of Two Waves of COVID-19 Disease with Impact of Vaccination as Optimal Control.

This paper is devoted to answering some questions using a mathematical model by analyzing India's first and second phases of the COVID-19 pandemic. A new mathematical model is introduced with a nonmonotonic incidence rate to incorporate the psychological effect of COVID-19 in society. The paper also discusses the local stability and global stability of an endemic equilibrium and a disease-free equilibrium. The basic reproduction number is evaluated using the proposed COVID-19 model for disease spread in India based on the actual data sets. The study of nonperiodic solutions at a positive equilibrium point is also analyzed. The model is rigorously studied using MATLAB to alert the decision-making bodies to hinder the emergence of any other pandemic outbreaks or the arrival of subsequent pandemic waves. This paper shows the excellent prediction of the first wave and very commanding for the second wave. The exciting results of the paper are as follows: (i) psychological effect on the human population has an impact on propagation; (ii) lockdown is a suitable technique mathematically to control the COVID spread; (iii) different variants produce different waves; (iv) the peak value always crosses its past value.