Cell-Free DNA Methylation of Selected Genes Allows for Early Detection of the Major Cancers in Women.
Sandra P NunesCatarina Moreira-BarbosaSofia SaltaSusana Palma de SousaInês PousaJúlio OliveiraMarta SoaresLicínio RegoTeresa DiasJéssica RodriguesLuís AntunesRui M HenriqueCarmen JerónimoPublished in: Cancers (2018)
CcfDNA's methylation assessment allows for simultaneous screening of BrC, CRC and LC, complementing current modalities, perfecting cancer suspects' triage, increasing compliance and cost-effectiveness.
Keyphrases
- cell free
- dna methylation
- genome wide
- papillary thyroid
- emergency department
- polycystic ovary syndrome
- gene expression
- circulating tumor
- squamous cell
- copy number
- squamous cell carcinoma
- pregnancy outcomes
- simultaneous determination
- lymph node metastasis
- mass spectrometry
- type diabetes
- high resolution
- metabolic syndrome
- liquid chromatography
- transcription factor
- genome wide identification
- bioinformatics analysis