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Exploring the mechanism of Ginkgo biloba L. leaves in the treatment of vascular dementia based on network pharmacology, molecular docking, and molecular dynamics simulation.

Jienuo PanJiqin TangJialin GaiYilan JinBingshun TangXiaohua Fan
Published in: Medicine (2023)
This study revealed the potential molecular mechanisms involved in the treatment of VD by GBLs using multi-ingredient, multi-target, and multi-pathway interactions, providing a theoretical basis for the clinical treatment and lead drug development of VD.
Keyphrases
  • molecular docking
  • molecular dynamics simulations
  • risk assessment
  • combination therapy