Sex-related differences in the clinical presentation of multiple system atrophy.

Fabian LeysSabine EschlböckNicole CampesePhilipp MahlknechtMarina PeballGeorg GoebelVictoria SidoroffFlorian KrismerRoberta GranataStefan KiechlWerner PoeweKlaus SeppiGregor K WenningAlessandra Fanciulli

Published in: Clinical autonomic research : official journal of the Clinical Autonomic Research Society (2024)

The available literature and findings of the present study indicate sex-related differences in the clinical presentation of MSA and its evolution over time, highlighting the importance of considering sex in symptom exploration, therapeutic decision-making, and future clinical trial design.

Keyphrases

clinical trial
decision making
systematic review
phase iii
placebo controlled