Heterogeneity of Necrotic Changes between Cortical and Cancellous Bone in Mandibular Osteoradionecrosis: A Histopathological Analysis of Resection Margin after Segmental Mandibulectomy.

Masaya Akashi Kazunobu HashikawaSatoshi WanifuchiJunya KusumotoManabu ShigeokaShungo FurudoiHiroto TerashiTakahide Komori

Published in: BioMed research international (2017)

Necrotic changes are more prevalent in cortices than in cancellous bones in mandibular osteoradionecrosis, probably due to a decrease of periosteal blood supply caused by radiotherapy.

Keyphrases

cone beam computed tomography
early stage
bone mineral density
single cell
locally advanced
radiation therapy
radiation induced
soft tissue
bone loss
bone regeneration