Impact of BMI on patient outcome in acute myeloid leukaemia patients receiving intensive induction therapy: a real-world registry experience.
Julius C EnßleSebastian WolfSebastian ScheichSarah WeberMichael KramerLeo RuhnkeChristoph SchliemannJan-Henrik MikeschStefan W KrauseTim SauerMaher HanounHans Christian ReinhardtSabrina KrausMartin KaufmannMathias HänelLars FranseckyAndreas BurchertAndreas NeubauerMartina CrysandtEdgar JostDirk NiemannKerstin Schäfer-EckartGerhard HeldUlrich KaiserMaxi WassMarkus SchaichCarsten Muller-TidowUwe PlatzbeckerClaudia D BaldusMartin BornhäuserChristoph RölligHubert Servenull nullBjörn SteffenPublished in: British journal of cancer (2023)
In conclusion, this study identifies obesity as an independent risk factor for worse OS in older AML patients undergoing curative IT most likely due to obesity-related comorbidities and not to dosing strategy.
Keyphrases
- weight gain
- insulin resistance
- patients undergoing
- metabolic syndrome
- weight loss
- acute myeloid leukemia
- high fat diet induced
- type diabetes
- liver failure
- body mass index
- case report
- physical activity
- genome wide
- dendritic cells
- bone marrow
- respiratory failure
- drug induced
- middle aged
- immune response
- gene expression
- hepatitis b virus
- allogeneic hematopoietic stem cell transplantation
- acute respiratory distress syndrome