EGFR Kinase Inhibiting Amino-enones for Breast Cancer; CADD Approach.

Deena Gladies Raymond MohanrajManikandan AlagumuthuSubha ChellamAbishek Suresh KumarTejaswini Nagaraj PoojariJeevitha Suresh KumarPalaniraja Subramaniam

Published in: Current computer-aided drug design (2024)

We recommend compounds 5b, 5c, 5g, and 5h for pre-clinical and clinical evaluation to establish them as future cancer therapeutics.

Keyphrases

clinical evaluation
tyrosine kinase
papillary thyroid
small cell lung cancer
epidermal growth factor receptor
squamous cell
signaling pathway
small molecule
current status
childhood cancer
protein kinase
lymph node metastasis
squamous cell carcinoma
young adults
breast cancer risk