Non-invasive transcutaneous auricular vagus nerve stimulation prevents postoperative ileus and endotoxemia in mice.

Gun-Soo HongAnne ZillekensBianca SchneikerDimitrios PantelisWouter J de JongeNico SchaeferJoerg C KalffSven Wehner

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)

tVNS prevents intestinal and systemic inflammation. Activation of the DMV indicates an afferent to efferent central circuitry of the tVNS stimulation and the beneficial effects of tVNS depend on an intact vagus nerve. tVNS may become a non-invasive approach for treatment of POI.

Keyphrases

patients undergoing
mouse model
high fat diet induced
type diabetes
lps induced
combination therapy
metabolic syndrome
inflammatory response
skeletal muscle