Hydrostatic Pressure-Regulated Cellular Calcium Responses.
Minami FukuchiKotaro OyamaHiroaki MizunoAkihisa MiyagawaKazuya KoumotoGaku FukuharaPublished in: Langmuir : the ACS journal of surfaces and colloids (2021)
Hydrostatic pressure control has attracted much attention and presents a still challenging objective from mechanobiological viewpoints. Herein, we reveal the calcium entry processes in HeLa cells by means of hydrostatic pressure spectroscopy. The steady-state fluorescence spectral data comprehensively elucidated the factors controlling the outcomes of the hydrostatic pressure-stimulated calcium entry behavior. The present work leads to a new perspective on ion regulations in living cells and an attractive alternative to conventional mechanostimuli.
Keyphrases
- living cells
- single molecule
- cell cycle arrest
- fluorescent probe
- induced apoptosis
- transcription factor
- genome wide
- type diabetes
- working memory
- high resolution
- electronic health record
- metabolic syndrome
- dna methylation
- cell death
- single cell
- machine learning
- mass spectrometry
- computed tomography
- gene expression
- weight loss
- magnetic resonance
- magnetic resonance imaging
- big data
- insulin resistance
- skeletal muscle
- energy transfer
- data analysis