Glomerular Filtration Rate as a Predictor of Outcome in Acute Coronary Syndrome Complicated by Atrial Fibrillation.
Domenico SantoroGuido GembilloGiuseppe AndòPublished in: Journal of clinical medicine (2020)
The close relationship between kidney and heart is well known. Cardiovascular impairment contributes to the worsening of renal function and kidney failure worsens cardiovascular health. Atrial fibrillation (AF) is a frequent issue in patients with Chronic Kidney Disease (CKD) and several studies have demonstrated that AF impacts negatively on their quality of life and outcomes. Understanding the mechanisms leading to the progression of CKD, new-onset AF and acute myocardial infarction (AMI) is a key issue. The evaluation of Glomerular Filtration Rate (GFR) could make the difference in this equilibrium and suggests specific strategies in the treatment of the population at major risk of cardiovascular events. This intriguing connection paves the way for necessary further investigations.
Keyphrases
- atrial fibrillation
- acute myocardial infarction
- cardiovascular events
- percutaneous coronary intervention
- acute coronary syndrome
- oral anticoagulants
- chronic kidney disease
- coronary artery disease
- catheter ablation
- left atrial
- left atrial appendage
- direct oral anticoagulants
- antiplatelet therapy
- heart failure
- cardiovascular disease
- left ventricular
- molecular dynamics
- case control
- adipose tissue
- venous thromboembolism