Advanced gastric cancer: CT radiomics prediction and early detection of downstaging with neoadjuvant chemotherapy.
Qinmei XuZeyu SunXiuli LiChen YeChangsheng ZhouLongjiang ZhangGuang Ming LuPublished in: European radiology (2021)
• Baseline contrast-enhanced computed tomography (CECT)-based radiomics features were predictive of pathological downstaging, allowing accurate identification of non-responders before therapy. • Restaging CECT-based radiomics features were predictive to achieve pDS after and even at an early stage of neoadjuvant chemotherapy. • Combination of baseline and restaging CECT-based radiomics features was promising for early detection and preoperative evaluation of pathological downstaging of AGC.
Keyphrases
- contrast enhanced
- neoadjuvant chemotherapy
- computed tomography
- diffusion weighted
- magnetic resonance imaging
- sentinel lymph node
- locally advanced
- magnetic resonance
- lymph node
- early stage
- diffusion weighted imaging
- dual energy
- positron emission tomography
- lymph node metastasis
- high resolution
- image quality
- stem cells
- mesenchymal stem cells