The prognostic impact of B7-H3 and B7-H4 in head and neck squamous cell carcinoma.
Mara BorgmannAgnes OettingFelix MeyerNikolaus MöckelmannConrad DrosteClara Marie von BargenChristina Möller-KoopMelanie WittKerstin BorgmannKai RothkammChristian BetzAdrian MünscherTill Sebastian ClauditzThorsten RieckmannPublished in: Journal of cancer research and clinical oncology (2022)
Despite a possible role in tumor immune escape, B7-H3 was associated with favorable prognosis in HPV-negative HNSCC in our cohort. The underlying mechanisms and a potential impact for B7-H3 targeting remain to be elucidated.