The prevalence of germline DICER1 pathogenic variation in cancer populations.

Jung KimKris Ann P SchultzDana Ashley HillDouglas R Stewart

Published in: Molecular genetics & genomic medicine (2019)

This is the largest comprehensive analysis of DICER1 pathogenic variation in adult and pediatric cancer populations using publicly available data. The observation of germline DICER1 variation with uterine corpus endometrial carcinoma merits additional investigation.

Keyphrases

papillary thyroid
childhood cancer
squamous cell
dna repair
risk factors
electronic health record
squamous cell carcinoma
big data
dna damage