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The Optimal Concentration of Formaldehyde is Key to Stabilizing the Pre-Fusion Conformation of Respiratory Syncytial Virus Fusion Protein.

Wei ZhangLu-Jing ZhangLu-Ting ZhanMin ZhaoGuang-Hua WuJun-Yu SiLi ChenXue LinYong-Peng SunMin LinChao YuMu-Jin FangYing-Bin WangZi-Zheng ZhengNing-Shao Xia
Published in: Viruses (2019)
Only the proper concentration of fixatives could stabilize pre-F and the optimal formaldehyde condition provides a potential reference for development of an inactivated RSV vaccine.
Keyphrases
  • respiratory syncytial virus
  • room temperature
  • crystal structure
  • risk assessment