The Optimal Concentration of Formaldehyde is Key to Stabilizing the Pre-Fusion Conformation of Respiratory Syncytial Virus Fusion Protein.
Wei ZhangLu-Jing ZhangLu-Ting ZhanMin ZhaoGuang-Hua WuJun-Yu SiLi ChenXue LinYong-Peng SunMin LinChao YuMu-Jin FangYing-Bin WangZi-Zheng ZhengNing-Shao XiaPublished in: Viruses (2019)
Only the proper concentration of fixatives could stabilize pre-F and the optimal formaldehyde condition provides a potential reference for development of an inactivated RSV vaccine.