Acanthosis nigricans in middle-age adults: A highly prevalent and specific clinical sign of insulin resistance.
Neri Alejandro Álvarez-VillalobosRené Rodríguez-GutiérrezGloria González-SaldivarAdriana Sánchez-GarcíaMinerva Gómez-FloresCarolina Quintanilla-SánchezAndrés Marcelo Treviño-ÁlvarezLeonardo Guadalupe Mancillas-AdameJosé Gerardo González-GonzálezPublished in: International journal of clinical practice (2019)
In middle-age adults, within the entire spectrum of carbohydrate tolerance, AN is highly prevalent and specific. This finding supports its assessment as a reliable and convenient clinical sign of IR. The understanding of AN behaviour through different carbohydrate tolerance strata, and its different locations, could lead to early detection of individuals at high metabolic risk or help direct a more pathophysiological treatment approach in patients with T2DM.
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