Causal effect between total cholesterol and HDL cholesterol as risk factors for chronic kidney disease: a mendelian randomization study.

Liu MiaoYan MinBin QiChuan-Meng ZhuJian-Hong ChenGuo-Xiong DengYong WangJian-Fei LiRong-Shan Li

Published in: BMC nephrology (2021)

The findings from this MR study indicate causal effects between TC, HDL-C and CKD. Decreased TC and elevated HDL-C may reduce the incidence of CKD but need to be further confirmed by using a genetic and environmental approach.

Keyphrases

chronic kidney disease
end stage renal disease
risk factors
magnetic resonance
genome wide
gene expression
risk assessment
climate change
copy number
contrast enhanced