Diabetes in HIV: the Link to Weight Gain.
Samuel S BailinJohn R KoethePublished in: Current HIV/AIDS reports (2022)
Recent studies confirm that PWH face an epidemic of obesity and T2DM, similar to the general population. Contemporary ART is associated with greater weight gain and may contribute to the risk of T2DM. Recent advances in medical weight loss therapy offer a way forward in the prevention and treatment of weight-associated T2DM. Weight gain is one of the biggest contributors to T2DM in PWH. Future studies on the role of adipose tissue distribution, adipose tissue function and clinical use of effective weight loss medications may change the paradigm of care for PWH.
Keyphrases
- weight gain
- weight loss
- glycemic control
- adipose tissue
- bariatric surgery
- birth weight
- roux en y gastric bypass
- body mass index
- healthcare
- gastric bypass
- insulin resistance
- hiv infected
- antiretroviral therapy
- type diabetes
- high fat diet
- human immunodeficiency virus
- hepatitis c virus
- hiv positive
- palliative care
- cardiovascular disease
- current status
- hiv aids
- metabolic syndrome
- hiv testing
- stem cells
- skeletal muscle
- physical activity
- mesenchymal stem cells
- combination therapy