Childhood BMI and Adult Type 2 Diabetes, Coronary Artery Diseases, Chronic Kidney Disease, and Cardiometabolic Traits: A Mendelian Randomization Analysis.

Ting-Ting GengCaren E SmithChangwei Li Tao Huang

Published in: Diabetes care (2018)

A genetic predisposition to higher childhood BMI was associated with increased risk of type 2 diabetes and CAD in adult life. These results provide evidence supportive of a causal association between childhood BMI and these outcomes.

Keyphrases

type diabetes
childhood cancer
body mass index
coronary artery
chronic kidney disease
early life
glycemic control
weight gain
young adults
genome wide
cardiovascular disease
coronary artery disease
pulmonary artery
end stage renal disease
insulin resistance
physical activity
pulmonary hypertension
weight loss