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Antidepressant Exposure and DNA Methylation: Insights from a Methylome-Wide Association Study.

E DavysonXueyi ShenFloris HuiderMark James AdamsK BorgesD McCartneyL BarkerJenny Van DongenDorret I BoomsmaAntoine WeihsHans Jörgen GrabeAnnemarie Luise KühnAlexander TeumerHenry VölzkeTianyu ZhuJaakko A KaprioMiina OllikainenFriederike S DavidSusanne MeinertFrederike SteinAndreas J ForstnerUdo DannlowskiTilo T J KircherA TapucDarina CzamaraElisabeth B BinderT BrücklAlex S F KwongPaul Darius YousefiCcy WongLouise ArseneaultHelen L FisherJonathan S MillSimon R CoxP RedmondTom Charles RussEdwin J C G van den OordKarolina A AbergBrenda W J H PenninxRiccardo E MarioniNaomi R WrayAndrew M McIntosh
Published in: medRxiv : the preprint server for health sciences (2024)
, which have roles in mitochondrial metabolism and neurite outgrowth. If replicated in future studies, targeting these genes could inform the design of more effective and better tolerated treatments for depression.
Keyphrases
  • dna methylation
  • genome wide
  • oxidative stress
  • major depressive disorder
  • depressive symptoms
  • gene expression
  • cancer therapy
  • current status
  • physical activity
  • drug delivery
  • bipolar disorder