A trimethoxy flavonoid isolated from stem extract of Tabebuia chrysantha suppresses angiogenesis in angiosarcoma.

Siva Prasad PandaUttam Prasad PanigrahyDsnbk PrasanthUma Sankar GorlaChakravarthi GuntupalliDeba Prasad PandaBikash Ranjan Jena

Published in: The Journal of pharmacy and pharmacology (2020)

The isolated flavonoid named TMF from T. chrysantha functions as specific regulators of target proteins of angiosarcoma. The STAT3-MMP9 signalling may be used as an effective prognostic marker of angiosarcoma.

Keyphrases

endothelial cells
oxidative stress
signaling pathway
cell proliferation
transcription factor
vascular endothelial growth factor
wound healing