Diagnostic Yield of Saliva for SARS-CoV-2 Molecular Testing in Children.

Dithi BanerjeeAnjana SasidharanAyah AbdulhamidEsmeralda M OroscoJennifer L WattsJennifer E SchusterAngela L MyersGina WeddleRangaraj Selvarangan

Published in: Journal of the Pediatric Infectious Diseases Society (2021)

Pediatric saliva specimen demonstrated high sensitivity (93%) and specificity (96.2%) compared to paired nasopharyngeal swabs (NPS) by Aptima SARS-CoV-2 Assay (Aptima). Viral loads were comparable in both specimen types. Saliva is a safe, noninvasive, and acceptable alternative specimen for SARS-CoV-2 detection in children.

Keyphrases

sars cov
respiratory syndrome coronavirus
young adults
high throughput
coronavirus disease
real time pcr
loop mediated isothermal amplification