The effect of magnesium sulfate on gene expression and serum level of inflammatory cytokines in coronary artery disease patients.

Fatemeh MohebiSamane OstadhadiMohammad Sadegh VaziriMarziyeh Hassanzadeh Shabnaz Koochakkhani Fariba Azarkish Hossein Farshidi Ebrahim Eftekhar

Published in: Inflammopharmacology (2023)

The results of our study demonstrate that 3-month magnesium sulfate administration (300 mg/day) to CAD patients could significantly decrease serum concentration and gene expression levels of IL-18 and TNF-α. Our findings support the potential beneficial effect of magnesium supplementation on alleviating CAD complications through modulating inflammatory cytokines.

Keyphrases

gene expression
coronary artery disease
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
dna methylation
prognostic factors
peritoneal dialysis
type diabetes
risk factors
patient reported outcomes
cardiovascular events
acute coronary syndrome
human health
aortic valve