Development of a Reversed-Phase UPLC Method for Assay of Fipronil Including Determination of Its Related Substances in Bulk Batches of Fipronil Drug Substance.

Published in: Journal of AOAC International (2024)

The new UPLC method is approximately 40% faster than the current Ph. Eur. monograph for fipronil assay and the new method provides reproducible retention of a common hydrolytic degradation product of fipronil.

Keyphrases

high throughput
simultaneous determination
emergency department
drug induced
solid phase extraction
molecularly imprinted
liquid chromatography