Risk factors for death during pulmonary tuberculosis treatment in Korea: a multicenter retrospective cohort study.
Yong Soo KwonYee Hyung KimJae-Uk SongKyeongman JeonJunwhi SongYon Ju RyuJae Chol ChoiHo Cheol KimWon-Jung KohPublished in: Journal of Korean medical science (2014)
The data regarding risk factors for death during tuberculosis (TB) treatment are inconsistent, and few studies examined this issue in Korea. The purpose of this study was to evaluate baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea. A multicenter retrospective cohort study of 2,481 patients who received TB treatment at eight hospitals from January 2009 to December 2010 was performed. Successful treatment included cure (1,129, 45.5%) and treatment completion (1,204, 48.5%) in 2,333 patients (94.0%). Unsuccessful treatment included death (85, 3.4%) and treatment failure (63, 2.5%) occurred in 148 patients (6.0%). In multivariate analysis, male sex, anemia, dyspnea, chronic heart disease, malignancy, and intensive care unit (ICU) admission were significant risk factors for death during TB treatment. Therefore, male sex, anemia, dyspnea, chronic heart disease, malignancy, and ICU admission could be baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea.
Keyphrases
- prognostic factors
- intensive care unit
- mycobacterium tuberculosis
- chronic kidney disease
- pulmonary tuberculosis
- end stage renal disease
- pulmonary hypertension
- emergency department
- newly diagnosed
- ejection fraction
- clinical trial
- hepatitis c virus
- deep learning
- electronic health record
- patient reported outcomes
- water quality