Scoring model based on the signature of non-m6A-related neoantigen-coding lncRNAs assists in immune microenvironment analysis and TCR-neoantigen pair selection in gliomas.

Wenbo ZhaoYibo WuFeihu ZhaoZhiyi XueWenyu LiuZenxin CaoZhimin ZhaoBin HuangMingzhi HanXingang Li

Published in: Journal of translational medicine (2022)

Our work suggests that non-m6A-related neoantigen-coding lncRNAs play an essential role in glioma progression and that screened TCR clonotypes might provide potential avenues for chimeric antigen receptor T cell (CAR-T) therapy for gliomas.

Keyphrases

high grade
regulatory t cells
stem cells
network analysis
climate change
human health
drug induced