The IL-1β-p65 axis stimulates quiescent odontogenic epithelial cell rests via TGF-β signalling to promote cell proliferation of the lining epithelia in radicular cysts: A laboratory investigation.
Ryoko NaganoYusuke NakakoShinsuke FujiiShintaro KawanoHidefumi MaedaTamotsu KiyoshimaPublished in: International endodontic journal (2024)
These results suggest that IL-1β-p65 signalling promotes odontogenic epithelial cell proliferation through suppressing TGF-β-Smad2 signalling, which would be involved in the pathogenesis of radicular cysts.