Psychotic symptoms are associated with elevated tau PET signal in the amygdala independent of Alzheimer's disease clinical severity and amyloid burden.

Aubrey S JohnsonGalen ZiaggiAnna C SmithHannah HoulihanLauren B HeuerDiana S GuzmánAmarachukwu OkaforEdward D HueyDaniel TalmasovFrank ProvenzanoWilliam C KreislPatrick J Laonull null

Published in: medRxiv : the preprint server for health sciences (2024)

Elevated tau in limbic regions may be relevant for psychotic symptoms in aging and AD.

Keyphrases

bipolar disorder
cerebrospinal fluid
sleep quality
functional connectivity
cognitive decline
positron emission tomography
risk factors
resting state
depressive symptoms
physical activity
pet imaging
prefrontal cortex
mild cognitive impairment
temporal lobe epilepsy