Quantitative and Qualitative Exploration of Meaningful Change on the Vineland Adaptive Behavior Scales (Vineland™-II) in Children and Adolescents with Autism Without Intellectual Disability Following Participation in a Clinical Trial.

Susanne ClinchStacie HudgensElizabeth GibbonsTom WillgossJanice SmithEla PolekClaire Burbridge

Published in: Patient related outcome measures (2023)

A change in standardized score of 4 to 8 points constitutes a within-person MCT on both VABS-ABC and novel VABS-2DC in those with ASD and no ID. A change of this, or more, was reported by the SPs in this trial to be meaningful and highly impactful upon the individuals with ASD and their family.

Keyphrases

intellectual disability
autism spectrum disorder
clinical trial
attention deficit hyperactivity disorder
phase ii
study protocol
phase iii
systematic review
open label
high resolution
placebo controlled