Therapeutic response and safety of the topical, sequential use of antiseptic, keratolytic, and pentamidine creams (3-PACK) on Leishmania (Viannia) braziliensis-infected mice.

Betsy Yaneth MuñozJulio Cesar MantillaPatricia R Escobar

Published in: Memorias do Instituto Oswaldo Cruz (2019)

The topical 3-PACK using 6% PMD was 67% effective in the treatment of CL by Leishmania (Viannia) braziliensis. Currently, work is ongoing to improve PMD isethionate formulation and to determine a dose-response.

Keyphrases

wound healing
drug delivery
high fat diet induced
type diabetes
metabolic syndrome
replacement therapy